Antistaphylococcal activity of LBM415, a new peptide deformylase inhibitor, compared with those of other agents.
نویسندگان
چکیده
The MICs of LBM415, a new peptide diformylase inhibitor, were </=0.06 to 4.0 microg/ml for 258 isolates of Staphylococcus aureus and coagulase-negative staphylococci. LBM415 MICs were similar irrespective of whether the strains were methicillin susceptible or resistant. All strains were also susceptible to vancomycin, linezolid, ranbezolid, daptomycin, oritavancin, and quinupristin-dalfopristin. LBM415 at the MIC was bacteriostatic after 24 h.
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 48 10 شماره
صفحات -
تاریخ انتشار 2004